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Based on CD4 + T cells and monocytes from a multi-ethnic cohort of 461 healthy individuals, susceptibility alleles for MS, rheumatoid arthritis, type 1 diabetes, and PD were found to be overrepresented in CD4 + T cells, while disease- and trait-associated cis-eQTLs associated with AD and PD were primarily overrepresented in monocytes (87)
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c-MET is formed by an extracellular alpha chain and a transmembrane beta chain that consists of the semaphorin (SEMA), PSI (plexins, semaphorins, and integrins), immunoglobulin-like (IPT), transmembrane (TM), juxtamembrane (JM), catalytic, and carboxyl terminal docking domains [3,4,5]