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If the rat chow diet was supplemented by N -acetylcysteine, noted elsewhere in this article to provide the rate-limiting reagent for glutathione synthesis and protect against Aβ42-associated OS in vivo (147), OS was significantly reduced

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In addition, due to the large difference in the concentration of specific coagulation factors in the blood of rodents and humans, the pathological processes that may lead to acute liver failure in mice is significantly different from the clinical pathological characteristics of human patients ( Mouse Models of Chronic Liver Injury Long-term chronic hepatotoxic substances, such as alcohol and metabolic diseases, are often the cause of chronic liver damage to the parenchymal cells of the liver