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228 In CCl 4 -induced liver fibrosis mice, FMT from metformin-treated mice alleviated liver fibrosis in recipient mice

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When Wnt or R-spondin-1 (RSPO1) is supplied, β-catenin accumulates, translocates to the nucleus, and activates T-cell Factor/Lymphoid Enhancer Factor (TCF/LEF) transcription of stemness genes (e.g., Leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5), SRY-Box Transcription Factor 9 (Sox9))