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PDF) Formation of N-Ethylmaleimide (NEM)-Glutathione Conjugate and N-Ethylmaleamic Acid Revealed by Mass Spectral Characterization of Intracellular and Extracellular Microbial Metabolites of NEM

Cytochrome P450 (CYP) is an ER-anchored family of heme-containing monooxygenases that can produce O 2 − and H 2 O 2 , and can cause the release of catalytic iron, and through Fenton reactions to the generation of potent oxidants

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Acute neurovisceral symptoms are due to increased activity of the first step of porphyrin synthesis and can be aggravated by certain drugs