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How D-Retro-Inverso Design Relates to Peptide Stability A D-retro-inverso peptide uses D-amino acid stereochemistry with sequence reversal to mimic side-chain orientation while changing the peptide backbone arrangement [5]

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Similarly, another two-center cohort study of 82 COVID-19 patients reported lower rates of respiratory failure, need for mechanical ventilation, and death when receiving 1,200 mg/day NAC [41]