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(Contraindications) Sermorelin is contraindicated in individuals with: Known allergy to Sermorelin acetate or its components.19 Pregnancy (Category C 13) or breastfeeding.7 Active malignancy (cancer), due to GH's cell proliferation potential.6 Untreated hypothyroidism, as it can blunt Sermorelin's effects.6 Acute critical illness.39 Certain pituitary conditions (e.g., GHD secondary to intracranial lesions were not studied in some key trials 13)

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[PubMed] [Google Scholar] Bernedo Paredes VE, Buchholz HG, Gartenschläger M, Breimhorst M, Schreckenberger M, Werhahn KJ (2015) Reduced D2/D3 receptor binding of extrastriatal and striatal regions in temporal lobe epilepsy