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In the brain regions prone to these detrimental features, a cascade of free radicals, inflammatory cytokines, and mitochondrial energy disruptions is initiated
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Examples include insufficient stores (found in preterm newborns and infants), inadequate intakes (a significant portion of the North American population consumes insufficient amounts of dietary copper, which is considered a risk factor for the development of MASLD), increased demands (such as during pregnancy, lactation, and wound healing), increased losses and malabsorption (which often occurs as a result of Roux-en-Y gastric bypass bariatric surgery) [14,15,34]