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Haemolysis: The haemoglobin S (HbS) molecule is more likely to form stiff, elongated chains when oxygen levels are low because of a beta haemoglobin mutation in the gene(Yu, 2022)

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In this study, we identified depletion of LIP in kidney macrophages as a driver of their pro-oxidative, proinflammatory, and profibrotic responses in CKD (Figure 9)