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Mitochondrial glutathione depletion directly correlates with oxidative damage to mitochondrial DNA, which accumulates during aging and impairs respiratory chain function

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Aptamer loading on carboxylic acid magnetic beads Five milligrams of Dynabeads MyOne carboxylic acid beads (MyOne) or 15 mg of Dynabeads M-270 carboxylic acid beads (M-270) were washed using MES buffer followed by resuspension of the beads in 300 µl of the same buffer